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"One of the greatest strength of Web as a platform is the ubiquity of access. A device, no matter how small or big, that ships without a built-in web browser is quickly becoming a thing of the past, a curiosity, a gadget at a severe disadvantage in the fiercely competitive landscape. This landscape is seeing a lot of experimentation in the physical screen size, aspect ratio and pixel density. Designing your structure around a few “well-known” pixel widths of a small subset of popular devices is a losing proposition."